Overuse or misuse may possibly end in overdose and/or Loss of life. It is necessary that patients only use medicines that happen to be prescribed for them on the dose they have been prescribed and don't give this medicine to any person else.

As with other opioids, tolerance and Actual physical and psychological dependence acquire with recurring dihydrocodeine use.

Constipation Dihydrocodeine slows down your digestion which can result in constipation. If you become constipated, check out to incorporate much more high-fibre foods inside your diet regime for instance fruits, greens and cereals.

AA. Characterization from the human cytochrome P450 enzymes involved in the metabolism of dihydrocodeine.

Ibuprofen applied to the pores and skin is less likely to affect other medicines than for those who take it as tablets, capsules, granules or liquid.

Your health practitioner will go over with you the way to slowly lessen your dose prior to stopping the medicine. It is important that you do not cease using the medicine all of a sudden as you may be much more likely to expertise withdrawal symptoms.

Get unexpected emergency medical help should you have any of these signs of an allergic reaction while using dihydrocodeine / phenylephrine: hives; challenging respiratory; swelling of one's face, lips, tongue, or throat.

Whereas changing codeine to morphine is a difficult and unrewarding endeavor, dihydrocodeine may be converted to dihydromorphine with pretty high yields (over 95%).

Having this medicine frequently, notably for more info the long time, may lead to addiction. Your medical doctor really should have explained howlong you're going to be using it for, when it is acceptable to halt and how To do that safely.

Warning ought to be taken when paracetamol is made use of concomitantly with flucloxacillin as concurrent intake has been involved with high anion gap metabolic acidosis, specifically in patients with risks factors (see section four.four).

Pethidine, dextromethorphan and tramadol are high-chance opioids for serotonin syndrome when made use of with serotonergic antidepressants.

Dihydrocodeine tablets need to be swallowed complete, and never broken, chewed or crushed. The administration of damaged, chewed or crushed tablets may perhaps lead to a quick launch and absorption of a most likely fatal dose of dihydrocodeine and should cause overdose effects (see section four.nine).

Renal side effects like granulomatous interstitial nephritis and acute renal failure have been documented almost never during dihydrocodeine administration.[Ref]

Your health practitioner should have mentioned with you, how long the training course of Dihydrocodeine tablets will last. They will arrange a system for stopping treatment. This could outline ways to gradually lessen the dose and stop having the medicine.